\documentclass{article}

\usepackage{amsmath}

\begin{document}

\begin{align}
	111 & \bullet 222                   \\
	    & \bullet 333 \begin{aligned}[t]
		                  444 & \bullet 555 \\
		                  666 & \bullet 777
	                  \end{aligned} \\
	    & \bullet 888                   \\
\end{align}

\end{document}
